Thor Medical enters supply agreement with NucliThera for thorium-228

November 20, 2025
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20.11.2025 07:30:01 CET | Thor Medical ASA | Non-regulatory press releases

Thor Medical ASA has signed a five-year frame agreement to supply NucliThera AS with thorium-228 (Th-228). The isotope will be used in NucliThera’s development programs for hematological cancers.

Led by Dr. Roy H. Larsen and Professor Emeritus Øyvind S. Bruland, NucliThera’s research team is advancing an early-stage development program targeting hematological cancers such as lymphoma and leukemia.

“We are working to develop targeted radionuclide therapies that can help cancer patients with a high unmet medical need. Reliable access to high-purity alpha-emitters is essential to advance these development programs, and with Thor Medical we expect to have a dependable domestic supplier of high-quality material,” says Dr. Roy H. Larsen, Co-Founder and Chair of NucliThera AS.

Dr. Larsen and Professor Bruland were jointly leading the development of the only alpha-emitting cancer pharmaceutical that so far has been approved by FDA – Xofigo for metastasized prostate cancer.

“We are proud to support NucliThera’s development program. Oslo has a strong and growing radiopharmaceutical community and ecosystem, and we are excited to be working with experienced industry leaders such as Dr. Larsen and Professor Bruland,” says Jasper Kurth, CEO of Thor Medical.

The thorium-228 will be supplied from AlphaOne, Thor Medical’s first commercial-scale isotope production facility, on track to begin operations in 2026. The supply agreement further adds to existing supply agreements for thorium-228 with Telix Pharmaceuticals, Oncoinvent, AdvanCell, ARTBIO, and two additional undisclosed partners.

In 2023, Thor Medical and NucliThera entered an agreement to transfer the former Nordic Nanovector's pipeline of patents ("Nanovector Patents") to NucliThera. Subject to the terms of the agreement, NucliThera AS assumed full ownership to the Nanovector Patents with Thor Medical retaining interest through an undisclosed profit-sharing in the event of successful commercialization of the patents. NucliThera continues the efforts to commercialize some of the patents, in addition to other new development programs in the company.  

Contact

Brede Ellingsæter, CFO and COO, Thor Medical ASA, +47 472 38 440, brede.ellingseter@thormedical.com

About Thor Medical ASA

Thor Medical is an emerging supplier of radionuclides, primarily alpha particle emitters, from naturally occurring thorium. Its proprietary production process requires no irradiation or use of nuclear reactors, and provides reliable, environmentally friendly, cost-efficient supply of alpha-emitters for the radiopharmaceutical industry. Thor Medical is headquartered in Oslo, Norway and listed on the Oslo Stock Exchange under the ticker symbol 'TRMED'.

About NucliThera AS

NucliThera is an R&D company developing targeted short, range radionuclides for treating hematological cancers like lymphoma and leukemia. High-energy alpha- and beta-radiating nuclides are linked to targeting monoclonal antibodies or small molecules. They bind to cancer cells killing them with minimal damage to surrounding healthy tissue.

The NucliThera research team is led by Dr. Roy H Larsen and Professor Emeritus Øyvind S Bruland. They have developed the only alpha-emitting cancer pharmaceutical approved by FDA so far – Xofigo against bone metastases from prostate cancer. Xofigo was acquired by Bayer Healthcare for US$ 2.9 billion in 2014.

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